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Tuesday, October 6, 2026 Week 6 · Early Edition

College football · ACC · 2026 · 2–2 against the closing spread

Louisville Cardinals

Next: Louisville vs. Florida State, Fri Oct 9, 7:00 PM ET. Louisville −3.5, opened −5.5, total 59.5.

2026 Season: How the Line Moved

WeekGameOpenedClosedMoveResultSpread
1at Ole Miss +6.5+6.5 — L 38–41Covered
2vs. Villanova —— — W 59–13—
3vs. SMU −1.5−2.5 −1.0 W 41–31Covered
4vs. Wake Forest −13.5−11 +2.5 L 27–30Didn't cover
5at NC State −7.5−3 +4.5 L 28–31Didn't cover
6vs. Florida State −5.5−3.5 +2.0 Upcoming—
7at Syracuse —— — Upcoming—

Louisville's consensus spread (median of U.S. sportsbooks and Kalshi) at our first look and at kickoff. A positive move means the market moved against Louisville. College football has no official injury report: availability news comes from reporting and coach statements.

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